CD120 is a topic that has generated great interest in today's society. From its origins until today, it has been the subject of study, debate and analysis in different areas. Its importance lies in its impact on people's daily lives, as well as its relevance in the academic, scientific, social, cultural fields, among others. This article seeks to address in a comprehensive and detailed manner different aspects related to CD120, offering a global and updated vision of this topic. Its origins, its evolution over time, its implications in current society and possible future perspectives will be explored.
There are two variants of the receptor, each encoded by a separate gene:
CD120a - TNFR1 - TNFR superfamily member 1A
CD120b - TNFR2 - TNFR superfamily member 1B
TNFR1 is the receptor type responsible for mediation of TNF-alpha induced sickness behavior, and is involved in neurotoxic processes. Elevated levels of TNFR1 has been found in severe mental disorders.